Wednesday 28.09.2022
15.00 - 15.15 – Official Opening (Michał Malewicz, Łukasiewicz – PORT)
Session 1 – Biological basis for cancer (Rare diseases)
15.15 - 15.50 Piotr Donizy (Wroclaw Medical University, Poland, online), Merkel cell carcinoma (MCC) - an ultra-rare and highly aggressive skin cancer: unmet needs and challenges in 2022
15.50 - 16.25 Agi Grigoriadis (King's College London, UK), Targeting transcriptional and signaling pathways in osteosarcoma pathogenesis and metastasis
16.25 - 17.00 Lucy Yates (Wellcome Trust Sanger Institute, UK), Spatial genomics maps the structure, character and evolution of cancer clones
17.00 - 17.35 Sussane Schlisio (Karolinska Institute, Sweden), Exploring drivers phenotypic plasticity in pheochromocytoma, paraganglioma and neuroblastoma progression
17:35 - 18.00 Break
18.00 - 19.00 Opening Keynote: Bożena Kamińska-Kaczmarek (Nencki Institute, Poland), Dissecting immune microenvironment of gliomas at single-cell resolution allows for reprogramming of tumor microenvironment and improves immunotherapy
Thursday 29.09.2022
Session 2 – Biological basis for cancer (DDR)
09.00 - 09.35 Małgorzata Krajewska (University College Cork, Ireland), Targeting Cyclin-dependent kinases for cancer therapy
09.35 - 10.10 Rachael Natrajan (Institute of Cancer Research, UK), Targeting SF3B1 mutant cancers
10.10 - 10.45 Özdemirhan Serçin (BioMed X, Germany), PARIS: A machine learning approach to find Synthetic Lethal Interactions in DNA Repair for Personalised Cancer Therapy
10.45 - 11.20 Break
Session 3 – Precision therapies in oncology (Immuno-oncology I)
11.20 - 11.55 Gabriela Kramer-Marek (Institute of Cancer Research, UK), Photoimmunotherapy – from bench to bedside
11.55 - 12.30 Sheeba Irshad (King's College London, UK), Mapping the Immune Landscape of High-Risk Chemotherapy Resistant Breast Cancers
12.30 - 13.05 Adrian Hayday (King's College London, UK), IMMUNE SURVEILLANCE OF CELL PATHOLOGY IN CANCER and COVID-19: from the clinic to the bench and back to the clinic
13.05 - 14.15 Break
Session 4 – Precision therapies in oncology (WiB-sponsored session)
14.15 - 14.50 WIB presentation 1 - Prof. Andrzej Dziembowski (IIMCB, Poland), Oncogenic mechanisms of DIS3 mutations
14.50 - 15.25 WIB presentation 2 - Prof. Jacek Jemielity (UoW, Poland), Chemically Modified mRNA for Therapeutic Applications
15.25 - 16.00 Piotr Kowalski (University College Cork, Ireland), Engineering messenger RNA nanotherapeutics for cancer therapy
16.00 - 16.35 Ivano Amelio (University of Konstanz, Germany), P53 prevents genomic instability preserving epigenetic integrity
16.35 - 17.00 Break
17.00 - 18.00 Keynote lecture: Stephen Schoenberger (La Jolla Insitute for Immunology, USA), Found in Translation: Enabling Personalized Immunotherapy through Academic/Clinical alliances
Friday 30.09.2022
Session 5 – Precision therapies in oncology (Immuno-oncology II)
09.30 - 10.05 Richard Beatson (University College London, UK, online), Glyco-immuno-regulation of epithelial disease
10.05 - 10.40 Grzegorz Chodaczek (Łukasiewicz – PORT, Poland), Anti-cancer activity of ex vivo expanded γδ T cells against glioblastoma multiforme
10.40 - 11.00 Break
Session 6 – Diagnostics in oncology (Biomarkers, new diagnostic methods/computational AI pathology)
11.00 - 11.35 Tomasz Zal (Immatics, USA), The tumor microenvironment in immunotherapy design and diagnostics – a personal journey
11.35 - 12.10 Anita Grigoriadis (King's College London, UK), Machine learning -based approaches capture novel prognostic morphological features in triple negative breast cancer patients
12.10 - 12.45 Roberto Salgado (University Hospital of Antwerp, Belgium), How can morphological evaluation of the immunesystem help in translational research?
12.45 - 13.20 Piotr Ziółkowski (Wroclaw Medical University, Poland) / Krzysztof Żółtański (Vialutions, Poland) / Andreas Pohling (Vialutions, Poland), New IT solution for guided reporting for pathologists diagnosing breast tumors
13.20 Official closure
