Can­cer Neu­ro­science of Brain Tumors

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AllergoOncology: Lessons Learned from the Allergy-Glioblastoma Connection
AllergoOncology: Lessons Learned from the Allergy-Glioblastoma Connection
AllergoOncology: Lessons Learned from the Allergy-Glioblastoma Connection

Frank Win­kler

Frank Win­kler grew up in Ham­burg, where he attend­ed the Wil­helm-Gym­na­si­um. After grad­u­at­ing from high school, he stud­ied human med­i­cine at the Uni­ver­si­ty of Ham­burg with stays in Freiburg, Cape Town and Lon­don at the Nation­al Hos­pi­tal for Neu­rol­o­gy and Neurosurgery.

In 1999, he began his train­ing at the Neu­ro­log­i­cal Clin­ic, Großhadern Hos­pi­tal of the Lud­wig Max­i­m­il­ian Uni­ver­si­ty of Munich. From 2002 to 2004, he com­plet­ed a post-doc­tor­al pro­gramme at Har­vard Uni­ver­si­ty. Dur­ing this time, he con­duct­ed research on the influ­ence of the vas­cu­lar sys­tem on brain tumours.

In 2012, he was appoint­ed pro­fes­sor of Exper­i­men­tal Neu­ro-Oncol­o­gy at the Depart­ment of Neu­rol­o­gy in Hei­del­berg, where he has been senior physi­cian since 2014. His Exper­i­men­tal Neu­ro-Oncol­o­gy research group is based at the Ger­man Can­cer Research Cen­tre (DKFZ) in Hei­del­berg. His wife Eva Win­kler is a spe­cial­ist in haematology/​oncology at Hei­del­berg Uni­ver­si­ty Hos­pi­tal and a mem­ber of the Ger­man Ethics Council.

The lab­o­ra­to­ry led by Frank Win­kler has used neu­ro­science meth­ods to devel­op a new under­stand­ing of malig­nant adult brain tumours, glioblas­tomas and brain metas­tases. Key dis­cov­er­ies from this work have helped to estab­lish the new field of can­cer neu­ro­science research. These include malig­nant mul­ti­cel­lu­lar tumour net­works that are high­ly func­tion­al and resilient and dri­ven by devel­op­men­tal neu­ro­bi­o­log­i­cal fac­tors, includ­ing pace­mak­er-like tumour cells in net­work nodes and exci­ta­to­ry synaps­es between brain neu­rons and var­i­ous incur­able brain tumour enti­ties that dri­ve brain tumour growth, inva­sion, and metastasis.

Frank Win­kler has ini­ti­at­ed clin­i­cal tri­als inves­ti­gat­ing how brain tumours in humans can be bet­ter con­trolled by dis­rupt­ing neu­ro-can­cer networks.

More infor­ma­tion can be found on Wikipedia.

Frank Win­kler grew up in Ham­burg, where he attend­ed the Wil­helm-Gym­na­si­um. After grad­u­at­ing from high school, he stud­ied human med­i­cine at the Uni­ver­si­ty of Ham­burg with stays in Freiburg, Cape Town and Lon­don at the Nation­al Hos­pi­tal for Neu­rol­o­gy and Neurosurgery.

In 1999, he began his train­ing at the Neu­ro­log­i­cal Clin­ic, Großhadern Hos­pi­tal of the Lud­wig Max­i­m­il­ian Uni­ver­si­ty of Munich. From 2002 to 2004, he com­plet­ed a post-doc­tor­al pro­gramme at Har­vard Uni­ver­si­ty. Dur­ing this time, he con­duct­ed research on the influ­ence of the vas­cu­lar sys­tem on brain tumours.

In 2012, he was appoint­ed pro­fes­sor of Exper­i­men­tal Neu­ro-Oncol­o­gy at the Depart­ment of Neu­rol­o­gy in Hei­del­berg, where he has been senior physi­cian since 2014. His Exper­i­men­tal Neu­ro-Oncol­o­gy research group is based at the Ger­man Can­cer Research Cen­tre (DKFZ) in Hei­del­berg. His wife Eva Win­kler is a spe­cial­ist in haematology/​oncology at Hei­del­berg Uni­ver­si­ty Hos­pi­tal and a mem­ber of the Ger­man Ethics Council.

The lab­o­ra­to­ry led by Frank Win­kler has used neu­ro­science meth­ods to devel­op a new under­stand­ing of malig­nant adult brain tumours, glioblas­tomas and brain metas­tases. Key dis­cov­er­ies from this work have helped to estab­lish the new field of can­cer neu­ro­science research. These include malig­nant mul­ti­cel­lu­lar tumour net­works that are high­ly func­tion­al and resilient and dri­ven by devel­op­men­tal neu­ro­bi­o­log­i­cal fac­tors, includ­ing pace­mak­er-like tumour cells in net­work nodes and exci­ta­to­ry synaps­es between brain neu­rons and var­i­ous incur­able brain tumour enti­ties that dri­ve brain tumour growth, inva­sion, and metastasis.

Frank Win­kler has ini­ti­at­ed clin­i­cal tri­als inves­ti­gat­ing how brain tumours in humans can be bet­ter con­trolled by dis­rupt­ing neu­ro-can­cer networks.

More infor­ma­tion can be found on Wikipedia.

Frank Winkler
Frank Win­kler, Uni­ver­sität­sklinik Hei­del­berg, GERMANY 

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